Machine Learning And Artificial Intelligence in Diabetes Prediction And Management: A Comprehensive Review of Models

Abstract

Diabetes mellitus is a chronic metabolic disorder with significant global prevalence and associated healthcare burdens, necessitating early detection and effective management strategies. The integration of Machine Learning (ML) and Artificial Intelligence (AI) has revolutionized diabetes care, offering innovative approaches to prediction, monitoring, and personalized management. This study conducted a systematic review of 82 high-quality peer-reviewed articles, following the PRISMA guidelines, to provide a comprehensive evaluation of ML and AI applications in diabetes prediction and management. The review highlights the widespread adoption of supervised learning models, such as Random Forest and Support Vector Machines (SVM), which consistently demonstrate high accuracy and reliability in predicting diabetes risk. Ensemble learning methods, particularly Gradient Boosting, emerged as superior techniques for predictive performance, while deep learning models, including Convolutional Neural Networks (CNNs) and Recurrent Neural Networks (RNNs), proved effective in analyzing unstructured data such as medical images and time-series glucose data. The integration of AI into wearable devices and mobile health applications has further enhanced real-time monitoring and glycemic control, bridging the gap between technological advancements and practical healthcare solutions. Despite these advancements, challenges such as data imbalance, limited external validation, and the need for explainable AI frameworks persist, underscoring the necessity for methodological rigor and standardization. This review provides critical insights into the current state, limitations, and opportunities of ML and AI in diabetes care, emphasizing their transformative potential in addressing this global health challenge.